CoraLite®594-conjugated ADC Monoclonal antibody
ADC Monoclonal Antibody for IF/ICC, FC (Intra)
Host / Isotype
Mouse / IgG1
Reactivity
Human, mouse, pig, rat
Applications
IF/ICC, FC (Intra)
Conjugate
CoraLite®594 Fluorescent Dye
CloneNo.
1A2B11
验证数据展示
经过测试的应用
Positive IF/ICC detected in | A431 cells |
Positive FC (Intra) detected in | A431 cells |
For other applications, we recommend the unconjugated version of this antibody, 67884-1-Ig
推荐稀释比
Application | Dilution |
---|---|
Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL594-67884 targets ADC in IF/ICC, FC (Intra) applications and shows reactivity with Human, mouse, pig, rat samples.
Tested Applications | IF/ICC, FC (Intra) Application Description |
Tested Reactivity | Human, mouse, pig, rat |
Immunogen | ADC fusion protein Ag31049 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | arginine decarboxylase |
Synonyms | AZIN2, AzI2, Arginine decarboxylase, ARGDC, Antizyme inhibitor 2 |
Calculated Molecular Weight | 460 aa, 50 kDa |
Observed Molecular Weight | 48-50 kDa |
GenBank Accession Number | BC028128 |
Gene Symbol | ADC |
Gene ID (NCBI) | 113451 |
Conjugate | CoraLite®594 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 588 nm / 604 nm |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | Q96A70 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Antizyme inhibitor 2 (AZIN2) is a member of the antizyme inhibitor family, witch is able to bind to AZs and inhibit their action on both ODC activity and polyamine uptake. AZIN2 is predominantly expressed in the brain and testis and localized in the endoplasmic reticulum-golgi intermediate compartment. Available data suggest its role in cell growth, spermiogenesis, vesicular trafficking and secretion. Accumulation of azin2 has also been observed in brains of patients with Alzheimer's disease (PMID: 19832840) . AZIN2 has 5 described insoforms produced by alternative splicing. The molecular weight of AZIN2 is about 50 kDa.
实验方案
Product Specific Protocols | |
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IF protocol for CL594 ADC antibody CL594-67884 | Download protocol |
FC protocol for CL594 ADC antibody CL594-67884 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |