验证数据展示
经过测试的应用
Positive IF/ICC detected in | MDCK cells, hTERT-RPE1 cells |
推荐稀释比
Application | Dilution |
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Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL594-17711 targets ARL13B in IF/ICC applications and shows reactivity with human, mouse, rat, canine samples.
Tested Applications | IF/ICC Application Description |
Tested Reactivity | human, mouse, rat, canine |
Immunogen | ARL13B fusion protein Ag12015 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | ADP-ribosylation factor-like 13B |
Synonyms | ARL2-like protein 1, ARL2L1, ARL2 like protein 1, ADP-ribosylation factor-like protein 2-like 1, ADP-ribosylation factor-like protein 13B |
Calculated Molecular Weight | 48 kDa |
GenBank Accession Number | BC094725 |
Gene Symbol | ARL13B |
Gene ID (NCBI) | 200894 |
RRID | AB_2883407 |
Conjugate | CoraLite®594 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 588 nm / 604 nm |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q3SXY8 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ARL13B, also named as ARL2L1, is a small ciliary G protein of the Ras superfamily. Localized in the cilia, it is required for cilium biogenesis and sonic hedgehog signaling. Defects in ARL13B are the cause of Joubert syndrome (JS) which is an autosomal recessive disorder characterized by a distinctive cerebellar malformation (PMID: 19906870). CoraLite594-Conjugated ARL13B antibody can be used to mark the cilia(red). Ex: 593nm, Em: 614nm
实验方案
Product Specific Protocols | |
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IF protocol for CL594 ARL13B antibody CL594-17711 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |