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验证数据展示

  • IF Staining of human tonsillitis using CL594-66443

    IF Staining of human tonsillitis using CL594-66443

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CoraLite®594 CD147 antibody (CL594-66443, Clone: 1G12B5 ) at dilution of 1:200.

  • IF Staining of human tonsillitis using CL594-66443

    IF Staining of human tonsillitis using CL594-66443

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CoraLite®594 CD147 antibody (CL594-66443, Clone: 1G12B5 ) at dilution of 1:200.

  • Featured Product
  • KD/KO验证

CoraLite®594-conjugated CD147 Monoclonal antibody

CD147 Monoclonal Antibody for IF-P
Cat No. CL594-66443

产品说明书

CloneNo. 1G12B5

宿主/亚型

Mouse / IgG1

种属反应性

human, pig

应用

IF-P

别名

5F7, Basigin, basigin (Ok blood group), BSG, CD147, Collagenase stimulatory factor, EMMPRIN, HAb18G, M6, OK, OK blood group antigen, TCSF

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite®594
规格: 

-/ -

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经过测试的应用

Positive IF-P detected inhuman tonsillitis tissue
Planning an IHC experiment? We recommend our IHCeasy CD147/BSG Ready-To-Use IHC Kit. CD147/BSG primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 66443-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL594-66443 targets CD147 in IF-P applications and shows reactivity with human, pig samples.

经测试应用 IF-P Application Description
经测试反应性 human, pig
免疫原 CD147 fusion protein Ag2619 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 basigin (Ok blood group)
别名 5F7, Basigin, basigin (Ok blood group), BSG, CD147, Collagenase stimulatory factor, EMMPRIN, HAb18G, M6, OK, OK blood group antigen, TCSF
计算分子量 385 aa, 42 kDa
观测分子量 45-50 kDa
GenBank蛋白编号BC009040
基因名称 CD147
Gene ID (NCBI) 682
RRIDAB_2883583
偶联类型 CoraLite®594 Fluorescent Dye
最大激发/发射波长588 nm / 604 nm
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP35613
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

BSG, also named as 5F7, Basigin, EMMPRIN, TCSF and CD147, plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS).CD147 may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. It seems to be a receptor for oligomannosidic glycans. CD147 is a receptor of CypA, inducing matrix metalloproteinase expression and mediating the degradation of the extracellular matrix, plays an important role in tumorigenesis and invasion in oral cancer. It has been considered as an objective and effective marker to predict invasion and prognosis in various cancers.

实验方案

Product Specific Protocols
IF protocol for CL594 CD147 antibody CL594-66443Download protocol
FC protocol for CL594 CD147 antibody CL594-66443Download protocol
Standard Protocols
Click here to view our Standard Protocols