Anti-Mouse CD3 (17A2)
CD3 Monoclonal Antibody for FC
Host / Isotype
Rat / IgG2b, kappa
Reactivity
Mouse
Applications
FC
Conjugate
Unconjugated
CloneNo.
17A2
验证数据展示
经过测试的应用
Positive FC detected in | C57BL/6 mouse splenocytes |
推荐稀释比
Application | Dilution |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
65077-1-Ig targets CD3 in FC applications and shows reactivity with Mouse samples.
Tested Applications | FC Application Description |
Tested Reactivity | Mouse |
Immunogen | γδTCR-positive T-T hybridoma D1 种属同源性预测 |
Host / Isotype | Rat / IgG2b, kappa |
Class | Monoclonal |
Type | Antibody |
Full Name | CD3 antigen, epsilon polypeptide |
Synonyms | AI504783, CD3, Cd3e, CD3epsilon, T3e |
GenBank Accession Number | BC098236 |
Gene Symbol | CD3ε |
Gene ID (NCBI) | 12501 |
RRID | AB_2918381 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Affinity purification |
UNIPROT ID | P22646 |
Storage Buffer | PBS with 0.09% sodium azide. |
Storage Conditions | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
CD3 is a multimeric protein associated with the T-cell receptor (TCR) to form a complex involved in antigen recognition and signal transduction (PMID: 15885124). CD3 is composed of CD3γ, δ, ε, and ζ chains (PMID: 1826255). It is expressed by thymocytes in a developmentally regulated manner, T cells, and some NK cells (PMID: 3289580). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).
实验方案
Product Specific Protocols | |
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FC protocol for CD3 antibody 65077-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |