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  • Featured Product
  • KD/KO Validated

CD38 Monoclonal antibody, PBS Only

CD38 Monoclonal Antibody for WB, IF/ICC, IF-P, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse

Applications

WB, IF/ICC, IF-P, ELISA

Conjugate

Unconjugated

CloneNo.

3C6G4

Cat no : 60006-1-PBS

Print datasheet

Synonyms

ADPRC 1, ADP ribosyl cyclase 1, 3C6G4, 2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase

验证数据展示

  • WB analysis using 60006-1-Ig (same clone as 60006-1-PBS)

    WB analysis using 60006-1-Ig (same clone as 60006-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 60006-1-Ig (CD38 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60006-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse spleen using 60006-1-Ig (same clone as 60006-1-PBS)

    IF Staining of mouse spleen using 60006-1-Ig (same clone as 60006-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse spleen tissue using CD38 antibody (60006-1-Ig, Clone: 3C6G4 ) at dilution of 1:400 and CoraLite®594-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L) (SA00013-3). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60006-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse spleen using 60006-1-Ig (same clone as 60006-1-PBS)

    IF Staining of mouse spleen using 60006-1-Ig (same clone as 60006-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse spleen tissue using CD38 antibody (60006-1-Ig, Clone: 3C6G4 ) at dilution of 1:400 and CoraLite®594-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L) (SA00013-3). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60006-1-PBS in a different storage buffer formulation.

  • IF Staining of Raji using 60006-1-Ig (same clone as 60006-1-PBS)

    IF Staining of Raji using 60006-1-Ig (same clone as 60006-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed Raji cells using CD38 antibody (60006-1-Ig, Clone: 3C6G4 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-1). This data was developed using the same antibody clone with 60006-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy CD38 Ready-To-Use IHC Kit. CD38 primary antibody included.

产品信息

60006-1-PBS targets CD38 in WB, IF/ICC, IF-P, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IF/ICC, IF-P, ELISA Application Description
Tested Reactivity human, mouse
Immunogen CD38 fusion protein Ag0487 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name CD38 molecule
Synonyms ADPRC 1, ADP ribosyl cyclase 1, 3C6G4, 2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase
Calculated Molecular Weight 300 aa, 34 kDa
Observed Molecular Weight 45 kDa
GenBank Accession NumberBC007964
Gene Symbol CD38
Gene ID (NCBI) 952
ENSEMBL Gene IDENSG00000004468
RRIDAB_716994
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP28907
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).