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  • Featured Product
  • KD/KO Validated

CoraLite® Plus 488-conjugated CORO1C Polyclonal antibody

CORO1C Polyclonal Antibody for IF/ICC

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF/ICC

Conjugate

CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-14749

Print datasheet

Synonyms

CRNN4, CRN2, Coronin-3, Coronin-1C, Coronin 3

验证数据展示

  • IF Staining of SH-SY5Y using CL488-14749

    IF Staining of SH-SY5Y using CL488-14749

    Immunofluorescent analysis of (-20°C Ethanol) fixed SH-SY5Y cells using CoraLite® Plus 488 CORO1C antibody (CL488-14749) at dilution of 1:200.

经过测试的应用

Positive IF/ICC detected inSH-SY5Y cells
For other applications, we recommend the unconjugated version of this antibody, 14749-1-AP

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-14749 targets CORO1C in IF/ICC applications and shows reactivity with human, mouse, rat samples.

Tested Applications IF/ICC Application Description
Tested Reactivity human, mouse, rat
Immunogen CORO1C fusion protein Ag6488 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name coronin, actin binding protein, 1C
Synonyms CRNN4, CRN2, Coronin-3, Coronin-1C, Coronin 3
Calculated Molecular Weight 53 kDa
Observed Molecular Weight 57 kDa
GenBank Accession NumberBC002342
Gene Symbol CORO1C
Gene ID (NCBI) 23603
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9ULV4
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CORO1C also known as HCRNN4, belongs to the WD repeat coronin family. CORO1C contains 5 N-terminal trp-asp (WD) repeats and a C-terminal coiled-coil motif. It was reported to regulate actin‐dependent processes by assembling F-actin. CORO1C promoted the invasion of breast cancer and glioma cells by specifically promoting the formation of invadopodia(PMID: 30974047).

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 CORO1C antibody CL488-14749Download protocol
Standard Protocols
Click here to view our Standard Protocols