验证数据展示
产品信息
60183-1-PBS targets Cytokeratin 20 in WB, IHC, IF/ICC, IF-P, Indirect ELISA applications and shows reactivity with human samples.
Tested Applications | WB, IHC, IF/ICC, IF-P, Indirect ELISA Application Description |
Tested Reactivity | human |
Immunogen | Cytokeratin 20 fusion protein Ag11336 种属同源性预测 |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Full Name | keratin 20 |
Synonyms | KRT20, keratin 20, K20, Cytokeratin-20, CK-20 |
Calculated Molecular Weight | 424 aa, 48 kDa |
Observed Molecular Weight | 46 kDa |
GenBank Accession Number | BC031559 |
Gene Symbol | Cytokeratin 20 |
Gene ID (NCBI) | 54474 |
RRID | AB_10858399 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P35900 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells. Keratin expression is highly regulated, tissue specific, and varies according to cell-state. Type I keratins consist of acidic, low molecular weight proteins with MW ranging from 40 kDa (KRT19) to 64 kDa (KRT9). Type 2 keratins consist of basic or neutral, high molecular weight proteins with MW from 52 kDa (KRT8) to 67 kDa (KRT18).Keratin 20 is a type I cytokeratin. It is a major cellular protein of mature enterocytes and goblet cells and is specifically found in the gastric and intestinal mucosa.