验证数据展示
产品信息
60183-1-PBS targets Cytokeratin 20 in WB, IHC, IF/ICC, IF-P, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IHC, IF/ICC, IF-P, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | Cytokeratin 20 fusion protein Ag11336 种属同源性预测 |
宿主/亚型 | Mouse / IgG2b |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | keratin 20 |
别名 | KRT20, keratin 20, K20, Cytokeratin-20, CK-20 |
计算分子量 | 424 aa, 48 kDa |
观测分子量 | 46 kDa |
GenBank蛋白编号 | BC031559 |
基因名称 | Cytokeratin 20 |
Gene ID (NCBI) | 54474 |
RRID | AB_10858399 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P35900 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells. Keratin expression is highly regulated, tissue specific, and varies according to cell-state. Type I keratins consist of acidic, low molecular weight proteins with MW ranging from 40 kDa (KRT19) to 64 kDa (KRT9). Type 2 keratins consist of basic or neutral, high molecular weight proteins with MW from 52 kDa (KRT8) to 67 kDa (KRT18).Keratin 20 is a type I cytokeratin. It is a major cellular protein of mature enterocytes and goblet cells and is specifically found in the gastric and intestinal mucosa.