验证数据展示
产品信息
66646-1-PBS targets EIF2AK2, PKR in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | EIF2AK2, PKR fusion protein Ag13010 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | eukaryotic translation initiation factor 2-alpha kinase 2 |
别名 | EIF2AK2, PKR, Eukaryotic translation initiation factor 2-alpha kinase 2, eIF-2A protein kinase 2, EC:2.7.11.1 |
计算分子量 | 551 aa, 62 kDa |
观测分子量 | 65-68 kDa |
GenBank蛋白编号 | BC093676 |
基因名称 | EIF2AK2 |
Gene ID (NCBI) | 5610 |
RRID | AB_2882004 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | P19525 |
储存缓冲液 | PBS Only |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2, also known as PKR or PRKR) is an important component of the host innate immuneantiviral response.The product of the HSAEIF2AK2 gene is a 68 kDa protein that is ubiquitously expressed at low levels. The N-terminal part of this protein contains two dsRNA binding motifs (dsRBM) .The C-terminal EIF2S1 kinase domain includes 12 sub-domains that are conserved in several Species(PMID:16954046 ).This antibody is specific to EIF2AK2.