验证数据展示
产品信息
66646-1-PBS targets EIF2AK2, PKR in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.
Tested Applications | WB, IHC, Indirect ELISA Application Description |
Tested Reactivity | human |
Immunogen | EIF2AK2, PKR fusion protein Ag13010 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | eukaryotic translation initiation factor 2-alpha kinase 2 |
Synonyms | EIF2AK2, PKR, Eukaryotic translation initiation factor 2-alpha kinase 2, eIF-2A protein kinase 2, EC:2.7.11.1 |
Calculated Molecular Weight | 551 aa, 62 kDa |
Observed Molecular Weight | 65-68 kDa |
GenBank Accession Number | BC093676 |
Gene Symbol | EIF2AK2 |
Gene ID (NCBI) | 5610 |
RRID | AB_2882004 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | P19525 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2, also known as PKR or PRKR) is an important component of the host innate immuneantiviral response.The product of the HSAEIF2AK2 gene is a 68 kDa protein that is ubiquitously expressed at low levels. The N-terminal part of this protein contains two dsRNA binding motifs (dsRBM) .The C-terminal EIF2S1 kinase domain includes 12 sub-domains that are conserved in several Species(PMID:16954046 ).This antibody is specific to EIF2AK2.