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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 67081-1-Ig (same clone as 67081-1-PBS)

    WB analysis using 67081-1-Ig (same clone as 67081-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67081-1-Ig (FRZB antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67081-1-PBS in a different storage buffer formulation.

FRZB Monoclonal antibody, PBS Only

FRZB Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67081-1-PBS

产品说明书

CloneNo. 2B4A1

宿主/亚型

Mouse / IgG1

种属反应性

Human, mouse

应用

WB, Indirect ELISA

别名

FIZ, FRE, Frezzled, FRITZ, frizzled related protein, Frizzled related protein 1, FRP, FRP 3, FRZB, FRZB 1, FRZB PEN, FRZB1, FZRB, hFIZ, sFRP 3, SFRP3, SRFP3

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67081-1-PBS targets FRZB in WB, Indirect ELISA applications and shows reactivity with Human, mouse samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human, mouse
免疫原 FRZB fusion protein Ag28147 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 frizzled-related protein
别名 FIZ, FRE, Frezzled, FRITZ, frizzled related protein, Frizzled related protein 1, FRP, FRP 3, FRZB, FRZB 1, FRZB PEN, FRZB1, FZRB, hFIZ, sFRP 3, SFRP3, SRFP3
计算分子量 325 aa, 36 kDa
观测分子量 36 kDa
GenBank蛋白编号BC027855
基因名称 FRZB
Gene ID (NCBI) 2487
RRIDAB_2882389
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ92765
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Frzb (also known as sFRP3) is a member of the secreted frizzled related protein (SFRP) family, originally identified as a chondrogenic factor during bone morphogenesis (PMID: 29209231). It was subsequently shown to be a regulator in Wnt signaling, and also have a role in regulating cell growth and differentiation in specific cell types. FRZB was seen to be acting as an oncogene in some cancer, such as metastatic renal cancer.