验证数据展示
产品信息
67481-1-PBS targets FURIN in WB, IHC, Indirect ELISA applications and shows reactivity with Human, Mouse samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | Human, Mouse |
免疫原 | FURIN fusion protein Ag13313 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | furin (paired basic amino acid cleaving enzyme) |
别名 | Dibasic processing enzyme, FUR, FURIN, PACE, PCSK3, SPC1 |
计算分子量 | 87 kDa |
观测分子量 | 90-110 kDa |
GenBank蛋白编号 | BC012181 |
基因名称 | FURIN |
Gene ID (NCBI) | 5045 |
RRID | AB_2882708 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | P09958 |
储存缓冲液 | PBS Only |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
FURIN, also named as FUR, PACE, PCSK3, SPC1, Kex2p, is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif. Furin is synthesized as an inactive zymogen that may minimize the occurrence of premature enzymatic activity that would lead to alternative protein activation or degradation. Glycosylation and other post-translational modifications can make the pre-pro furin run at 100-110 kDa, the mature furin at 98-95 kDa and shed furin at 90 kDa.