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FURIN Monoclonal antibody, PBS Only

FURIN Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, Mouse

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1D1B9

Cat no : 67481-1-PBS

Print datasheet

Synonyms

Dibasic processing enzyme, FUR, FURIN, PACE, PCSK3, SPC1

验证数据展示

  • WB analysis using 67481-1-Ig (same clone as 67481-1-PBS)

    WB analysis using 67481-1-Ig (same clone as 67481-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67481-1-Ig (FURIN antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67481-1-PBS in a different storage buffer formulation.

  • IHC staining of human placenta using 67481-1-Ig (same clone as 67481-1-PBS)

    IHC staining of human placenta using 67481-1-Ig (same clone as 67481-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 67481-1-Ig (FURIN antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67481-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with FURIN antibody included
  • IHC staining of human placenta using 67481-1-Ig (same clone as 67481-1-PBS)

    IHC staining of human placenta using 67481-1-Ig (same clone as 67481-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 67481-1-Ig (FURIN antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67481-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with FURIN antibody included
Planning an IHC experiment? We recommend our IHCeasy FURIN Ready-To-Use IHC Kit. FURIN primary antibody included.

产品信息

67481-1-PBS targets FURIN in WB, IHC, Indirect ELISA applications and shows reactivity with Human, Mouse samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity Human, Mouse
Immunogen FURIN fusion protein Ag13313 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name furin (paired basic amino acid cleaving enzyme)
Synonyms Dibasic processing enzyme, FUR, FURIN, PACE, PCSK3, SPC1
Calculated Molecular Weight 87 kDa
Observed Molecular Weight 90-110 kDa
GenBank Accession NumberBC012181
Gene Symbol FURIN
Gene ID (NCBI) 5045
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP09958
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

FURIN, also named as FUR, PACE, PCSK3, SPC1, Kex2p, is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif. Furin is synthesized as an inactive zymogen that may minimize the occurrence of premature enzymatic activity that would lead to alternative protein activation or degradation. Glycosylation and other post-translational modifications can make the pre-pro furin run at 100-110 kDa, the mature furin at 98-95 kDa and shed furin at 90 kDa.