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CoraLite® Plus 488-conjugated Ferritin light chain Polyclonal antibody

Ferritin light chain Polyclonal Antibody for IF/ICC

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF/ICC

Conjugate

CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-10727

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Synonyms

Ferritin L subunit, Ferritin light chain, ferritin, light polypeptide, FTL



经过测试的应用

Positive IF/ICC detected inHepG2 cells

This antibody is not recommended for WB detection of brain sample.

Planning an IHC experiment? We recommend our IHCeasy FTL Ready-To-Use IHC Kit. FTL primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 10727-1-AP

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-10727 targets Ferritin light chain in IF/ICC applications and shows reactivity with human, mouse, rat samples.

Tested Applications IF/ICC Application Description
Tested Reactivity human, mouse, rat
Immunogen Ferritin light chain fusion protein Ag1149 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name ferritin, light polypeptide
Synonyms Ferritin L subunit, Ferritin light chain, ferritin, light polypeptide, FTL
Calculated Molecular Weight 19 kDa
GenBank Accession NumberBC008439
Gene Symbol Ferritin light chain
Gene ID (NCBI) 2512
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP02792
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

FTL belongs to the ferritin family. It stores iron in a soluble, non-toxic, readily available form. FTL is important for iron homeostasis. It plays a role in delivery of iron to cells. FTL mediates iron uptake in capsule cells of the developing kidney. Mutation of FTL will cause hereditary hyperferritinemia-cataract syndrome (HHCS) or neurodegeneration with brain iron accumulation type 3 (NBIA3). Ferritin light polypeptide (FTL) and ferritin heavy polypeptide (FTH1) were the main constituents the striatum and cerebellar cortex revealed.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 Ferritin light chain antibody CL488-10727Download protocol
Standard Protocols
Click here to view our Standard Protocols