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CoraLite® Plus 647-conjugated HEXIM1 Polyclonal antibody
HEXIM1 Polyclonal Antibody for FC (Intra)
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
FC (Intra)
Conjugate
CoraLite® Plus 647 Fluorescent Dye
验证数据展示
Planning an IHC experiment? We recommend our IHCeasy HEXIM1 Ready-To-Use IHC Kit. HEXIM1 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 15676-1-AP
产品信息
CL647-15676 targets HEXIM1 in FC (Intra) applications and shows reactivity with human, mouse, rat samples.
| Tested Applications | FC (Intra) Application Description |
| Tested Reactivity | human, mouse, rat |
| Immunogen | HEXIM1 fusion protein Ag8144 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | hexamethylene bis-acetamide inducible 1 |
| Synonyms | Cardiac lineage protein 1, CLP1, EDG1, FLJ13562, HEXIM1, HIS1, MAQ1, Menage a quatre protein 1, Protein HEXIM1 |
| Calculated Molecular Weight | 41 kDa |
| Observed Molecular Weight | 70 kDa |
| GenBank Accession Number | BC006460 |
| Gene Symbol | HEXIM1 |
| Gene ID (NCBI) | 10614 |
| Conjugate | CoraLite® Plus 647 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 654 nm / 674 nm |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O94992 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
HEXIM1, also named CLP1, EDG1, HIS1 or MAQ1, is best known as the inhibitor of positive transcription elongation factor b, which regulates the transcription elongation of RNA polymerase II and controls 60-70% of mRNA synthesis. HEXIM1 regulates NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity. Previous studies showed that HEXIM1 interacts with two key p53 regulators, nucleophosmin and HDM2, implying a possible connection between HEXIM1 and the p53 signaling pathway.The mainstream MW of this protein is 65-70 kDa and 54 kDa ( PMID: 33627647, PMID: 20976203, PMID: 28254838).
实验方案
| Product Specific Protocols | |
|---|---|
| FC protocol for CL Plus 647 HEXIM1 antibody CL647-15676 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |