验证数据展示
产品信息
66041-1-PBS targets HSP60 as part of a matched antibody pair:
MP50644-1: 66041-1-PBS capture and 66041-2-PBS detection (validated in Cytometric bead array)
Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
Tested Applications | WB, IHC, IF/ICC, IP, Cytometric bead array, Indirect ELISA Application Description |
Tested Reactivity | human, mouse, rat |
Immunogen | HSP60 fusion protein Ag7848 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | heat shock 60kDa protein 1 (chaperonin) |
Synonyms | HSPD1, GROEL, EC:5.6.1.7, CPN60, Chaperonin 60 |
Calculated Molecular Weight | 61 kDa |
Observed Molecular Weight | 60 kDa |
GenBank Accession Number | BC003030 |
Gene Symbol | HSP60 |
Gene ID (NCBI) | 3329 |
RRID | AB_11041709 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P10809 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
HSPD1, also known as HSP60, belongs to the chaperonin family and acts as a chaperone to enhance cell survival under physiological stresses. Hsp60 has been shown to be connected with many aspects of cell functions such as protein folding and assembling of polypeptide chains in mitochondria. Recently it has been reported that HSP60 is associated with apoptosis or inhibition of cancer cell growth. (21822415)