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验证数据展示

  • WB analysis of HepG2 using 66137-1-Ig (same clone as 66137-1-PBS)

    WB analysis of HepG2 using 66137-1-Ig (same clone as 66137-1-PBS)

    HepG2 cells were subjected to SDS PAGE followed by western blot with 66137-1-Ig (IFITM2-specific antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66137-1-PBS in a different storage buffer formulation.

  • WB analysis of recombinant protein using 66137-1-Ig (same clone as 66137-1-PBS)

    WB analysis of recombinant protein using 66137-1-Ig (same clone as 66137-1-PBS)

    IFITM1 (Lane 1), IFITM2 (Lane 2) and IFITM3 (Lane 3) fusion proteins (20ng/lane) were subjected to SDS-PAGE followed by western blot with IFITM2 monoclonal antibody (66137-1-Ig) at dilution of 1:10,000. This data was developed using the same antibody clone with 66137-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

IFITM2-Specific Monoclonal antibody, PBS Only

IFITM2-Specific Monoclonal Antibody for WB, Indirect ELISA
Cat No. 66137-1-PBS

产品说明书

CloneNo. 3D5F7

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, Indirect ELISA

别名

IFITM2, IFITM 2, DSPA2c, 3D5F7, 18D

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy IFITM2 Ready-To-Use IHC Kit. IFITM2 primary antibody included.

产品信息

66137-1-PBS targets IFITM2-Specific in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 interferon induced transmembrane protein 2 (1-8D)
别名 IFITM2, IFITM 2, DSPA2c, 3D5F7, 18D
观测分子量 15 kDa
GenBank蛋白编号NM_006435
基因名称 IFITM2
Gene ID (NCBI) 10581
RRIDAB_2881536
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ01629
储存缓冲液 PBS Only
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IFITM2, also named as 1-8D, belongs to the CD225 family. It is an IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication. IFITM2 induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. It is overexpressed in colon carcinoma. IFITM2 is a novel pro-apoptotic gene that will provide new insights into the regulated cellular pathways to death.(PMID:19544527) This antibody is specific to IFTIM2.