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验证数据展示

  • IHC staining of human pancreas using 66198-1-Ig (same clone as 66198-1-PBS)

    IHC staining of human pancreas using 66198-1-Ig (same clone as 66198-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas tissue slide using 66198-1-Ig (Insulin Antibody) at dilution of 1:5000 (under 10x lens). This data was developed using the same antibody clone with 66198-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with Insulin antibody included
  • IHC staining of human pancreas using 66198-1-Ig (same clone as 66198-1-PBS)

    IHC staining of human pancreas using 66198-1-Ig (same clone as 66198-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas tissue slide using 66198-1-Ig (Insulin Antibody) at dilution of 1:5000 (under 40x lens). This data was developed using the same antibody clone with 66198-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with Insulin antibody included
  • IF Staining of human pancreas using 66198-1-Ig (same clone as 66198-1-PBS)

    IF Staining of human pancreas using 66198-1-Ig (same clone as 66198-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human pancreas tissue using 66198-1-Ig (Insulin antibody) at dilution of 1:100 and CoraLite594-Conjugated Goat Anti-Mouse IgG(H+L). The α cells of pancreas was labelled in green with 15954-1-AP (Glucagon antibody). This data was developed using the same antibody clone with 66198-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse pancreas using 66198-1-Ig (same clone as 66198-1-PBS)

    IF Staining of mouse pancreas using 66198-1-Ig (same clone as 66198-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse pancreas tissue using INS antibody (66198-1-Ig, Clone: 4B6A7 ) at dilution of 1:400 and CoraLite®594-Conjugated Goat Anti-Mouse IgG(H+L), Somatostatin antibody (24496-1-AP, green). This data was developed using the same antibody clone with 66198-1-PBS in a different storage buffer formulation.

INS Monoclonal antibody, PBS Only

INS Monoclonal Antibody for IHC, IF-P, Indirect ELISA
Cat No. 66198-1-PBS

产品说明书

CloneNo. 4B6A7

宿主/亚型

Mouse / IgG2a

种属反应性

human, mouse, rat

应用

IHC, IF-P, Indirect ELISA

别名

insulin, 4B6A7

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy Insulin Ready-To-Use IHC Kit. Insulin primary antibody included.

产品信息

66198-1-PBS targets INS in IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 IHC, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 INS fusion protein Ag8630 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 INS
别名 insulin, 4B6A7
计算分子量 110 aa, 12 kDa
GenBank蛋白编号BC005255
基因名称 INS
Gene ID (NCBI) 3630
RRIDAB_2881591
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP01308
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

INS is a peptide hormone, produced by beta cells of the pancreas, and is central to regulating carbohydrate and fat metabolism in the body. It participates in glucose utilization, protein synthesis and in the formation and storage of neutral lipids. INS is synthesized as a precursor molecule, pro-INS, which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form INS, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Defects in INS results in type 1 diabetes mellitus. INS may also exist 36 kDa form corresponding to the hexameric INS form.