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INS Monoclonal antibody, PBS Only

INS Monoclonal Antibody for Indirect ELISA,IHC,IF

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse, rat

Applications

Indirect ELISA,IHC,IF

Conjugate

Unconjugated

CloneNo.

4B6A7

Cat No : 66198-1-PBS

Print datasheet

Synonyms

ILPR, INS, IRDN

验证数据展示

  • IHC staining of human pancreas using 66198-1-Ig (same clone as 66198-1-PBS)

    IHC staining of human pancreas using 66198-1-Ig (same clone as 66198-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas tissue slide using 66198-1-Ig (Insulin Antibody) at dilution of 1:5000 (under 10x lens). This data was developed using the same antibody clone with 66198-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with Insulin antibody included
  • IHC staining of human pancreas using 66198-1-Ig (same clone as 66198-1-PBS)

    IHC staining of human pancreas using 66198-1-Ig (same clone as 66198-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas tissue slide using 66198-1-Ig (Insulin Antibody) at dilution of 1:5000 (under 40x lens). This data was developed using the same antibody clone with 66198-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with Insulin antibody included
  • IF Staining of human pancreas using 66198-1-Ig (same clone as 66198-1-PBS)

    IF Staining of human pancreas using 66198-1-Ig (same clone as 66198-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human pancreas tissue using 66198-1-Ig (Insulin antibody) at dilution of 1:100 and CoraLite594-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). The α cells of pancreas was labelled in green with 15954-1-AP (Glucagon antibody). This data was developed using the same antibody clone with 66198-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse pancreas using 66198-1-Ig (same clone as 66198-1-PBS)

    IF Staining of mouse pancreas using 66198-1-Ig (same clone as 66198-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse pancreas tissue using INS antibody (66198-1-Ig, Clone: 4B6A7 ) at dilution of 1:400 and CoraLite®594-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L), Somatostatin antibody (24496-1-AP, green). This data was developed using the same antibody clone with 66198-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy Insulin Ready-To-Use IHC Kit. Insulin primary antibody included.

产品信息

66198-1-PBS targets INS in IF, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications Indirect ELISA,IHC,IF Application Description
Tested Reactivity human, mouse, rat
Immunogen INS fusion protein Ag8630 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name INS
Synonyms ILPR, INS, IRDN
Calculated Molecular Weight 110 aa, 12 kDa
GenBank Accession NumberBC005255
Gene Symbol INS
Gene ID (NCBI) 3630
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP01308
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

INS is a peptide hormone, produced by beta cells of the pancreas, and is central to regulating carbohydrate and fat metabolism in the body. It participates in glucose utilization, protein synthesis and in the formation and storage of neutral lipids. INS is synthesized as a precursor molecule, pro-INS, which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form INS, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Defects in INS results in type 1 diabetes mellitus. INS may also exist 36 kDa form corresponding to the hexameric INS form.