MUC16/CA125 Monoclonal antibody

MUC16/CA125 Monoclonal Antibody for IHC, ELISA
Cat No. 60261-1-Ig

产品说明书

CloneNo. 2B11B10

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

IHC, ELISA

MUC16, MUC16,CA125, MUC-16, MUC 16, CA125

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive IHC detected inhuman ovary tumor tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

IHCSee 2 publications below

产品信息

60261-1-Ig targets MUC16/CA125 in IHC, ELISA applications and shows reactivity with human samples.

经测试应用 IHC, ELISA Application Description
文献引用应用IHC
经测试反应性 human
文献引用反应性human
免疫原 Peptide 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 mucin 16, cell surface associated
别名 MUC16, MUC16,CA125, MUC-16, MUC 16, CA125
计算分子量 1519 kDa
GenBank蛋白编号NM_024690
基因名称 MUC16
Gene ID (NCBI) 94025
RRIDAB_2881382
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ8WXI7
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

MUC16, also named as CA125, is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. It is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller "subunits" being described by some investigators. The antibody recognizes the C-term of MUC16.

实验方案

Product Specific Protocols
IHC protocol for MUC16/CA125 antibody 60261-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanIHC

Cancer Lett

MUC16 C terminal-induced secretion of tumor-derived IL-6 contributes to tumor-associated Treg enrichment in pancreatic cancer.

Authors - Kun Fan
humanIHC

Int J Oncol

Lewis antigen‑negative pancreatic cancer: An aggressive subgroup.

Authors - Chen Liu
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