验证数据展示
产品信息
60261-1-PBS targets MUC16/CA125 in IHC, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | IHC, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | Peptide 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | mucin 16, cell surface associated |
别名 | MUC16, MUC16,CA125, MUC-16, MUC 16, CA125 |
计算分子量 | 1519 kDa |
GenBank蛋白编号 | NM_024690 |
基因名称 | MUC16 |
Gene ID (NCBI) | 94025 |
RRID | AB_2881382 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | Q8WXI7 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
MUC16, also named as CA125, is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. It is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller "subunits" being described by some investigators. The antibody recognizes the C-term of MUC16.