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验证数据展示

  • WB analysis using 66920-1-Ig (same clone as 66920-1-PBS)

    WB analysis using 66920-1-Ig (same clone as 66920-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66920-1-Ig (NFKB2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66920-1-PBS in a different storage buffer formulation.

  • WB analysis using 66920-1-Ig (same clone as 66920-1-PBS)

    WB analysis using 66920-1-Ig (same clone as 66920-1-PBS)

    N/A This data was developed using the same antibody clone with 66920-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 66920-1-Ig (same clone as 66920-1-PBS)

    IHC staining of human liver cancer using 66920-1-Ig (same clone as 66920-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 66920-1-Ig (NFKB2 antibody) at dilution of 1:300 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66920-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with NFKB2 antibody included
  • Featured Product
  • KD/KO验证

NFKB2 Monoclonal antibody, PBS Only

NFKB2 Monoclonal Antibody for WB, IHC, ELISA
Cat No. 66920-1-PBS

产品说明书

CloneNo. 6A10E9

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, IHC, ELISA

别名

LYT10, LYT 10, H2TF1, DNA-binding factor KBF2, DNA binding factor KBF2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy NFKB2 Ready-To-Use IHC Kit. NFKB2 primary antibody included.

产品信息

66920-1-PBS targets NFKB2 in WB, IHC, ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, ELISA Application Description
经测试反应性 human
免疫原 NFKB2 fusion protein Ag28543 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
别名 LYT10, LYT 10, H2TF1, DNA-binding factor KBF2, DNA binding factor KBF2
计算分子量 97 kDa
观测分子量 100 kDa
GenBank蛋白编号BC002844
基因名称 NFKB2
Gene ID (NCBI) 4791
ENSEMBL Gene IDENSG00000077150
RRIDAB_2882247
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ00653
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. NFKB2 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p100 and generation of p52 by a cotranslational processing. The proteasome-mediated process ensures the production of both p52 and p100 and preserves their independent function. P52 binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of genes involved in immune response and acute phase reactions. P52 and p100 are respectively the minor and major form; the processing of p100 being relatively poor. Isoform p49 is a subunit of the NF-kappa-B protein complex, which stimulates the HIV enhancer in synergy with p65.