NeutraControl VEGF165 Monoclonal antibody

NeutraControl VEGF165 Monoclonal Antibody for ELISA, Non-Neutralization
Cat No. 69525-1-Ig

产品说明书

CloneNo. 7E9F4

宿主/亚型

Mouse / IgG1

种属反应性

Human

应用

ELISA, Non-Neutralization

L VEGFA, MVCD1, Vascular permeability factor, VEGF, VEGF A, VEGFA, VPF

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


Planning an IHC experiment? We recommend our IHCeasy VEGFA/VEGF Ready-To-Use IHC Kit. VEGFA/VEGF primary antibody included.

产品信息

69525-1-Ig targets VEGF165 in ELISA, Non-Neutralization applications and shows reactivity with Human samples.

经测试应用 ELISA, Non-Neutralization Application Description
经测试反应性 Human
免疫原 human Humankine VEGF165 protein HZ-1038 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 vascular endothelial growth factor A
别名 L VEGFA, MVCD1, Vascular permeability factor, VEGF, VEGF A, VEGFA, VPF
基因名称 VEGFA
Gene ID (NCBI) 7422
RRIDAB_2918856
偶联类型 Unconjugated
形式 Lyophilized Powder
纯化方式Protein G purification
储存缓冲液 Sterile PBS , pH 7.4
内毒素<0.1 EU/μg
复溶This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use.
稳定性与储存Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.

背景介绍

VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are associated with microvascular complications of diabetes type 1 (MVCD1). VEGFA has 17 isoforms with MW from 16 to 45 kDa. Some isoforms have homodimer forms (e.g.; VEGFA189 38 kDa or VEFGA110 34 kDa). VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids (PMID:15602010 ).

This antibody is a neutralizing control antibody for VEGF165, the immunogen is the same as Neutrakine 69025-1-Ig but could not neutralize human VEGF165.

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