NeutraKine®IL-27 Monoclonal antibody

NeutraKine®IL-27 Monoclonal Antibody for ELISA, Neutralization
Cat No. 69034-1-Ig

产品说明书

CloneNo. 2H2A2

宿主/亚型

Mouse / IgG1

种属反应性

Human

应用

ELISA, Neutralization

IL 27, IL 27 A, IL 27 subunit alpha, IL 27A, IL27, IL-27, IL27 A, IL27A, IL27p28, IL30, interleukin 27, Interleukin 27 subunit alpha, p28

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


Neutralization

产品信息

69034-1-Ig targets NeutraKine®IL-27 in ELISA, Neutralization applications and shows reactivity with Human samples.

经测试应用 ELISA, Neutralization Application Description
经测试反应性 Human
免疫原 human HumankineIL-27 protein HZ-1275 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 interleukin 27
别名 IL 27, IL 27 A, IL 27 subunit alpha, IL 27A, IL27, IL-27, IL27 A, IL27A, IL27p28, IL30, interleukin 27, Interleukin 27 subunit alpha, p28
基因名称 IL-27
Gene ID (NCBI) 246778
RRIDAB_3670460
偶联类型 Unconjugated
形式 Lyophilized Powder
纯化方式Protein A purification
UNIPROT IDQ8NEV9
储存缓冲液 Sterile PBS , pH 7.4
内毒素<0.1 EU/μg
复溶This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use.
稳定性与储存Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.

背景介绍

IL-27 is a heterodimeric cytokine composed of two subunits: IL-27a and IL-27b. IL-27 acts on various cell types, including T cells, B cells, macrophages, dendritic cells, natural killer (NK) cells and non-hematopoietic cells. IL-27 plays a critical role in the early regulation of T helper type 1 initiation, and enhances proliferation of naive CD4+T cells and naive B cells. It, however, also exerts anti-inflammatory functions by inhibiting the development of Th17 cells and inducing IL-10 producing type 1 regulatory T cells. IL-27 is a potentially promising cytokine for therapeutic approaches on various human diseases.

This antibody is used to neutralize the bioactivity of IL-27.

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