验证数据展示
产品信息
60322-1-PBS targets P-selectin / CD62P in WB, IP, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IP, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | P-selectin / CD62P fusion protein Ag4124 种属同源性预测 |
宿主/亚型 | Mouse / IgG2b |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | selectin P (granule membrane protein 140kDa, antigen CD62) |
别名 | CD62P, P-selectin, GMP140, GMP 140, CD62 antigen-like family member P |
计算分子量 | 830 aa, 91 kDa |
观测分子量 | 140 kDa, 105-110 kDa |
GenBank蛋白编号 | BC028067 |
基因名称 | CD62P |
Gene ID (NCBI) | 6403 |
RRID | AB_2881433 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P16109 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.