P-selectin / CD62P Monoclonal antibody

P-selectin / CD62P Monoclonal Antibody for WB, IP, ELISA
Cat No. 60322-1-Ig

产品说明书

CloneNo. 3G2C7

宿主/亚型

Mouse / IgG2b

种属反应性

human and More (2)

应用

WB, IP, ELISA and More (1)

CD62P, P-selectin, GMP140, GMP 140, CD62 antigen-like family member P

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inhuman peripheral blood platelets, Jurkat cells
Positive IP detected inK-562 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:2000-1:10000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

60322-1-Ig targets P-selectin / CD62P in WB, IF, IP, ELISA applications and shows reactivity with human samples.

经测试应用 WB, IP, ELISA Application Description
文献引用应用WB, IF
经测试反应性 human
文献引用反应性human, mouse, rat
免疫原 P-selectin / CD62P fusion protein Ag4124 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 selectin P (granule membrane protein 140kDa, antigen CD62)
别名 CD62P, P-selectin, GMP140, GMP 140, CD62 antigen-like family member P
计算分子量 830 aa, 91 kDa
观测分子量 140 kDa, 105-110 kDa
GenBank蛋白编号BC028067
基因名称 CD62P
Gene ID (NCBI) 6403
RRIDAB_2881433
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP16109
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.

实验方案

Product Specific Protocols
WB protocol for P-selectin / CD62P antibody 60322-1-IgDownload protocol
IP protocol for P-selectin / CD62P antibody 60322-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Cell Metab

Targeting Erbin-mitochondria axis in platelets/megakaryocytes promotes B cell-mediated antitumor immunity

Authors - Zilong Zhang
ratWB

Acta Biomater

Rescuing ischemic stroke by biomimetic nanovesicles through accelerated thrombolysis and sequential ischemia-reperfusion protection.

Authors - Wenyan Yu
humanWB

Front Oncol

An Essential NRP1-Mediated Role for Tagln2 in Gastric Cancer Angiogenesis.

Authors - Hongwei Jin
mouseWB

Front Oncol

Platelet Membranes Coated Gold Nanocages for Tumor Targeted Drug Delivery and Amplificated Low-Dose Radiotherapy.

Authors - Mingzhu Chen
humanFC

Commun Biol

Generation and characterization of cardiac valve endothelial-like cells from human pluripotent stem cells.

Authors - LinXi Cheng
mouseWB

Front Bioeng Biotechnol

Nano-Platelets as an Oxygen Regulator for Augmenting Starvation Therapy Against Hypoxic Tumor.

Authors - Chunyu Huang
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