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P53 Recombinant antibody, PBS Only

P53 Uni-rAbTM Recombinant Antibody for WB, IHC, IF/ICC, FC (Intra), Indirect ELISA
Cat No. 80077-1-PBS

产品说明书

CloneNo. 2H13

宿主/亚型

Rabbit / IgG

种属反应性

human, zebrafish

应用

WB, IHC, IF/ICC, FC (Intra), Indirect ELISA

TP53, 2H13, Antigen NY-CO-13, tumor protein p53, Tumor suppressor p53

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


Planning an IHC experiment? We recommend our IHCeasy P53 Ready-To-Use IHC Kit. P53 primary antibody included.

产品信息

80077-1-PBS targets P53 in WB, IHC, IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with human, zebrafish samples.

经测试应用 WB, IHC, IF/ICC, FC (Intra), Indirect ELISA Application Description
经测试反应性 human, zebrafish
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 tumor protein p53
别名 TP53, 2H13, Antigen NY-CO-13, tumor protein p53, Tumor suppressor p53
计算分子量 44 kDa
观测分子量53 kDa
GenBank蛋白编号BC003596
基因名称 P53
Gene ID (NCBI) 7157
RRIDAB_2918862
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP04637
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TP53, also known as P53 and NY-CO-13, belongs to the p53 family and has 9 isoforms. In SDS-Page, the observed molecular weight is about 53 kDa. TP53 acts as a tumor suppressor in many tumor types, including growth arrest or apoptosis depending on the physiological circumstances and cell types. It is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. TP53 Localizes in the nucleus in most cells but found in the cytoplasm in some cells. (PMID: 26166714; PMID: 25225161)

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