验证数据展示
产品信息
67529-1-PBS targets PAX6 in WB, IHC, IF, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications | WB, IHC, Indirect ELISA Application Description |
Cited Applications | IF |
Tested Reactivity | human, mouse, rat |
Cited Reactivity | rat |
Immunogen | PAX6 fusion protein Ag29977 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | paired box 6 |
Synonyms | Pax-6, PAX 6, Paired box protein Pax-6, Paired box protein Pax 6, paired box 6 |
Calculated Molecular Weight | 47 kDa |
Observed Molecular Weight | 47 kDa |
GenBank Accession Number | BC011953 |
Gene Symbol | PAX6 |
Gene ID (NCBI) | 5080 |
RRID | AB_2882748 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P26367 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PAX6, a paired domain and homeodomain-containing transcription factor. Interaction with TRIM11 leads to ubiquitination of PAX6 and its proteasomal degradation. PAX6 is one of the earliest genes expressed in the eye field and considered a master control gene for retinal and eye development. PAX6 also regulates the development of the olfactory, central nervous systems, pituitary, and pancreas. PAX6 mutations can cause complex ocular disorders such as aniridia and Peter's anomaly.