Biotin-conjugated Progesterone Receptor Monoclonal antibody

Progesterone Receptor Monoclonal Antibody for IHC
Cat No. Biotin-66300

产品说明书

CloneNo. 3D1D12

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

IHC

PGR, PRGR, PR, NR3C3, 3D1D12

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Biotin
规格: 

-/ -


经过测试的应用

Positive IHC detected inhuman ovary tumor tissue, human breast cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Planning an IHC experiment? We recommend our IHCeasy PR Ready-To-Use IHC Kit. PR primary antibody included.

推荐稀释比

应用推荐稀释比
Immunohistochemistry (IHC)IHC : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

Biotin-66300 targets Progesterone Receptor in IHC applications and shows reactivity with human samples.

经测试应用 IHC Application Description
经测试反应性 human
免疫原 Progesterone Receptor fusion protein Ag22992 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 progesterone receptor
别名 PGR, PRGR, PR, NR3C3, 3D1D12
计算分子量 933 aa, 99 kDa
GenBank蛋白编号NM_000926
基因名称 Progesterone Receptor
Gene ID (NCBI) 5241
RRIDAB_2883069
偶联类型 Biotin
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP06401
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

PGR (Progesterone Receptor), also named as NR3C3 and PR, belongs to the nuclear hormone receptor family and NR3 subfamily. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. The ER and PR status has been used as a predictor of breast carcinoma responsiveness to endocrine therapy and as a prognostic indicator for early recurrence.

实验方案

Product Specific Protocols
IHC protocol for Biotin Progesterone Receptor antibody Biotin-66300Download protocol
Standard Protocols
Click here to view our Standard Protocols
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