验证数据展示
产品信息
66854-1-PBS targets Phospho-RIPK1 (Ser161) in WB, IHC, IF/ICC, FC (Intra), ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IHC, IF/ICC, FC (Intra), ELISA Application Description |
经测试反应性 | human |
免疫原 | Peptide 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
别名 | Phospho RIPK1, p RIPK1 Ser161, p RIPK1 (Ser161), p RIPK1, Phospho RIPK1 (Ser161) |
计算分子量 | 76 kDa |
观测分子量 | 74 kDa, 45 kDa |
GenBank蛋白编号 | NM_003804 |
基因名称 | RIPK1 |
Gene ID (NCBI) | 8737 |
RRID | AB_2882194 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q13546 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
RIPK1(Receptor-interacting serine/threonine-protein kinase 1) is primarily involved in mediating TNF-R1-induced cell activation, apoptosis and necroptosis and belongs to a novel class of kinases thatfunction in cell survival and cell death mechanisms(PMID:22685397 ).It has 2 isoforms produced by alternative splicing.It also can exist as the protein with lower molecular weight about 25kd and 45kd in HAEC and HUVEC(PMID:22685397).