CoraLite® Plus 488-conjugated TGN46 Polyclonal antibody

TGN46 Polyclonal Antibody for IF/ICC

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

IF/ICC and More (1)

Conjugate

CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-13573

Print datasheet

Synonyms

TGN38, TGN38 homolog, TGN46, TGN48, TGN51, TGOLN2, trans golgi network protein 2, TTGN2



经过测试的应用

Positive IF/ICC detected inHeLa cells
For other applications, we recommend the unconjugated version of this antibody, 13573-1-AP

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)/ICCIF/ICC : 1:400-1:1600
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

IFSee 1 publications below

产品信息

CL488-13573 targets TGN46 in IF/ICC applications and shows reactivity with human samples.

Tested Applications IF/ICC Application Description
Cited ApplicationsIF
Tested Reactivity human
Cited Reactivitymouse
Immunogen TGN46 fusion protein Ag4470 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name trans-golgi network protein 2
Synonyms TGN38, TGN38 homolog, TGN46, TGN48, TGN51, TGOLN2, trans golgi network protein 2, TTGN2
Calculated Molecular Weight 447 aa, 47 kDa
Observed Molecular Weight 90-100 kDa
GenBank Accession NumberBC028219
Gene Symbol TGN46
Gene ID (NCBI) 10618
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO43493
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

TGN46 (TGOLN2), the human homologue of rat Tgn38, is a transmembrane glycoprotein predominantly localized to the TGN (trans-Golgi network). TGN is a major secretory pathway sorting station for proteins and lipids. TGN46 may be involved in regulating membrane traffic to and from TGN. Alternatively spliced transcript variants encode different TGN46 isoforms. TGN46 has an apparent molecular mass of 100-150 kDa, suggesting extensive O- and N-glycosylations.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 TGN46 antibody CL488-13573Download protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseIF

Elife

TMC7 deficiency causes acrosome biogenesis defects and male infertility in mice

Authors - Jing Wang