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验证数据展示

  • WB analysis of HepG2 using 66191-1-Ig (same clone as 66191-1-PBS)

    WB analysis of HepG2 using 66191-1-Ig (same clone as 66191-1-PBS)

    WB result of VAPB antibody (66191-1-Ig, 1:5000) with si-control and si-VAPB transfected HepG2 cells. This data was developed using the same antibody clone with 66191-1-PBS in a different storage buffer formulation.

  • WB analysis using 66191-1-Ig (same clone as 66191-1-PBS)

    WB analysis using 66191-1-Ig (same clone as 66191-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66191-1-Ig (VAPB antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66191-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 66191-1-Ig (same clone as 66191-1-PBS)

    IF Staining of HepG2 using 66191-1-Ig (same clone as 66191-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using VAPB antibody (66191-1-Ig, Clone: 4F6A6 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66191-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 66191-1-Ig (same clone as 66191-1-PBS)

    IHC staining of human breast cancer using 66191-1-Ig (same clone as 66191-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66191-1-Ig (VAPB Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 66191-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with VAPB antibody included
  • IHC staining of human breast cancer using 66191-1-Ig (same clone as 66191-1-PBS)

    IHC staining of human breast cancer using 66191-1-Ig (same clone as 66191-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66191-1-Ig (VAPB Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 66191-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with VAPB antibody included
  • Featured Product
  • KD/KO验证

VAPB Monoclonal antibody, PBS Only

VAPB Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 66191-1-PBS

产品说明书

CloneNo. 4F6A6

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

ALS8, VAMP associated protein B/C, VAMP B, VAMP B/VAMP C, VAMP C, VAP B, VAP B/VAP C, VAP C, VAPB

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy VAPB Ready-To-Use IHC Kit. VAPB primary antibody included.

产品信息

66191-1-PBS targets VAPB in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原 VAPB fusion protein Ag6313 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 VAMP (vesicle-associated membrane protein)-associated protein B and C
别名 ALS8, VAMP associated protein B/C, VAMP B, VAMP B/VAMP C, VAMP C, VAP B, VAP B/VAP C, VAP C, VAPB
计算分子量 27 kDa
观测分子量30-32 kDa
GenBank蛋白编号BC001712
基因名称 VAPB
Gene ID (NCBI) 9217
RRIDAB_2881586
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDO95292
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Vesicle-associated membrane protein-associated protein B (VAPB) is an integral membrane protein localized to the endoplasmic reticulum (ER) membrane. VAPB has been implicated in various cellular processes, including ER stress, the unfolded protein response (UPR) and calcium homeostasis regulation. The mutations in the gene of VAPB cause amyotrophic lateral sclerosis 8 (ALS8) and some other related forms of motor neuron disease including late onset spinal muscular atrophy.