验证数据展示
经过测试的应用
Positive IF-P detected in | human tonsillitis tissue |
推荐稀释比
应用 | 推荐稀释比 |
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Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL594-60200 targets ZAP70 in IF-P applications and shows reactivity with human samples.
经测试应用 | IF-P Application Description |
经测试反应性 | human |
免疫原 | ZAP70 fusion protein Ag7943 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | zeta-chain (TCR) associated protein kinase 70kDa |
别名 | 70 kDa zeta associated protein, FLJ17670, FLJ17679, SRK, STD, Syk related tyrosine kinase, Tyrosine protein kinase ZAP 70, TZK, ZAP 70, ZAP70 |
计算分子量 | 70 kDa |
GenBank蛋白编号 | BC039039 |
基因名称 | ZAP70 |
Gene ID (NCBI) | 7535 |
ENSEMBL Gene ID | ENSG00000115085 |
RRID | AB_2883439 |
偶联类型 | CoraLite®594 Fluorescent Dye |
最大激发/发射波长 | 588 nm / 604 nm |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P43403 |
储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Zeta-associated protein (ZAP)-70, a member of the Syk family of tyrosine kinases, plays an important role in T-cell receptor signaling, natural killer (NK) cell activation and early B-cell development. ZAP-70 is expressed in a subset of cases of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) with unmutated immunoglobulin heavy-chain variable region (IgVH) genes and is associated with poor clinical outcome.
实验方案
Product Specific Protocols | |
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IF protocol for CL594 ZAP70 antibody CL594-60200 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |