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  • Featured Product
  • KD/KO Validated

ZC3HAV1 Monoclonal antibody, PBS Only

ZC3HAV1 Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1G10B9

Cat no : 66413-1-PBS

Print datasheet

Synonyms

FLB6421, ZAP, ZC3H2, ZC3HAV1, ZC3HDC2, Zinc finger antiviral protein

验证数据展示

  • WB analysis of HEK-293 using 66413-1-Ig (same clone as 66413-1-PBS)

    WB analysis of HEK-293 using 66413-1-Ig (same clone as 66413-1-PBS)

    WB result of ZC3HAV1 antibody (66413-1-Ig; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-ZC3HAV1 transfected HEK-293 cells. This data was developed using the same antibody clone with 66413-1-PBS in a different storage buffer formulation.

  • WB analysis of Jurkat using 66413-1-Ig (same clone as 66413-1-PBS)

    WB analysis of Jurkat using 66413-1-Ig (same clone as 66413-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 66413-1-Ig (ZC3HAV1 Antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66413-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 66413-1-Ig (same clone as 66413-1-PBS)

    IHC staining of human kidney using 66413-1-Ig (same clone as 66413-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 66413-1-Ig (ZC3HAV1 Antibody) at dilution of 1:300 (under 40x lens). This data was developed using the same antibody clone with 66413-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 66413-1-Ig (same clone as 66413-1-PBS)

    IF Staining of HepG2 using 66413-1-Ig (same clone as 66413-1-PBS)

    Immunofluorescent analysis of (-20℃ Ethanol ) fixed HepG2 cells using 66413-1-Ig(ZC3HAV1 antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66413-1-PBS in a different storage buffer formulation.

产品信息

66413-1-PBS targets ZC3HAV1 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen ZC3HAV1 fusion protein Ag10364 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name zinc finger CCCH-type, antiviral 1
Synonyms FLB6421, ZAP, ZC3H2, ZC3HAV1, ZC3HDC2, Zinc finger antiviral protein
Calculated Molecular Weight699aa,78 kDa; 902aa,101 kDa
Observed Molecular Weight 100 kDa
GenBank Accession NumberBC025308
Gene Symbol ZC3HAV1
Gene ID (NCBI) 56829
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ7Z2W4
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

he zinc-finger antiviral protein (ZAP) was originally identifed from a rat cDNA library due to its conferring resistance to retroviruses. ZC3HAV1 is a CCCH-type zinc finger protein, it may primarily function to inhibit viral gene expression and induce an innate immunity to viral infection. Alternative splicing occurs at this locus and two variants, each encoding distinct isoforms.