• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • IF Staining of rat liver using PE-66692

    IF Staining of rat liver using PE-66692

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded rat liver tissue using PE ASGR1 antibody (PE-66692, Clone: 1G5F5 ) at dilution of 1:100. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Featured Product
  • KD/KO验证

PE-conjugated ASGR1 Monoclonal antibody

ASGR1 Monoclonal Antibody for IF-P
Cat No. PE-66692

产品说明书

CloneNo. 1G5F5

宿主/亚型

Mouse / IgG1

种属反应性

human, mouse, rat, pig

应用

IF-P

别名

asialoglycoprotein receptor 1, HL-1, Asgpr1, ASGP-R 1, ASGPR 1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  PE
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

经过测试的应用

Positive IF-P detected inrat liver tissue
Planning an IHC experiment? We recommend our IHCeasy ASGR1 Ready-To-Use IHC Kit. ASGR1 primary antibody included.

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

PE-66692 targets ASGR1 in IF-P applications and shows reactivity with human, mouse, rat, pig samples.

经测试应用 IF-P Application Description
经测试反应性 human, mouse, rat, pig
免疫原 ASGR1 fusion protein Ag2310 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 asialoglycoprotein receptor 1
别名 asialoglycoprotein receptor 1, HL-1, Asgpr1, ASGP-R 1, ASGPR 1
计算分子量 291 aa, 33 kDa
观测分子量 42-46 kDa
GenBank蛋白编号BC032130
基因名称 ASGR1
Gene ID (NCBI) 432
RRIDAB_3674012
偶联类型 PE Fluorescent Dye
最大激发/发射波长496 nm, 565 nm / 578 nm
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP07306
储存缓冲液 PBS with 0.09% sodium azide and 0.5% BSA , pH 7.3
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

Asialoglycoprotein receptor (ASGPR), also known as the hepatic galactose/N-acetylglucosamine (GlcNAc) receptor or Ashwell receptor, is a C-type lectin expressed exclusively in hepatic parenchymal cells. ASGPR consists of two subunits, a major subunit (ASGR1, HL-1) and a minor subunit (ASGR2, HL-2), and specifically recognizes terminal β-linked galactose or GlcNAc on circulating glycoproteins or cells. This receptor plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins that contain terminal galactose or GlcNAc residues. ASGPR may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery.

实验方案

Product Specific Protocols
IF protocol for PE ASGR1 antibody PE-66692Download protocol
Standard Protocols
Click here to view our Standard Protocols