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- KD/KO Validated
CoraLite® Plus 488-conjugated CP110 Polyclonal antibody
CP110 Polyclonal Antibody for IF/ICC
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
IF/ICC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
验证数据展示
经过测试的应用
Positive IF/ICC detected in | HeLa cells |
Planning an IHC experiment? We recommend our IHCeasy CP110 Ready-To-Use IHC Kit. CP110 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 12780-1-AP
推荐稀释比
Application | Dilution |
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Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL488-12780 targets CP110 in IF/ICC applications and shows reactivity with human samples.
Tested Applications | IF/ICC Application Description |
Tested Reactivity | human |
Immunogen | CP110 fusion protein Ag3489 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | CP110 protein |
Synonyms | Centrosomal protein of 110 kDa, CP110, CP110 protein, DKFZp781G1416, KIAA0419 |
Calculated Molecular Weight | 991 aa, 111 kDa |
Observed Molecular Weight | 113 kDa |
GenBank Accession Number | BC036654 |
Gene Symbol | CP110 |
Gene ID (NCBI) | 9738 |
RRID | AB_2919060 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | O43303 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
CP110, also named as CCP110 and KIAA0419, is an 110kDa protein. This gene is different to the gene CEP110 (geneID:11064; CNTRL). CP110 is a centriolar protein that positively regulates centrioleduplication while restricting centriole elongation and ciliogenesis. And it acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation.
实验方案
Product Specific Protocols | |
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IF protocol for CL Plus 488 CP110 antibody CL488-12780 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |