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IFIT3 Monoclonal antibody, PBS Only

IFIT3 Monoclonal Antibody for WB,Indirect ELISA,IHC,IF

Host / Isotype

Mouse / IgG2a

Reactivity

Human

Applications

WB,Indirect ELISA,IHC,IF

Conjugate

Unconjugated

CloneNo.

2C8B10

Cat No : 67208-1-PBS

Print datasheet

Synonyms

CIG 49, CIG49, GARG 49, IFI 60K, IFI60, IFIT 3, IFIT 4, IFIT3, IFIT4, IRG2, ISG 60, ISG60, RIG G

验证数据展示

  • WB analysis using 67208-1-Ig (same clone as 67208-1-PBS)

    WB analysis using 67208-1-Ig (same clone as 67208-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67208-1-Ig (IFIT3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67208-1-PBS in a different storage buffer formulation.

  • IHC staining of human spleen using 67208-1-Ig (same clone as 67208-1-PBS)

    IHC staining of human spleen using 67208-1-Ig (same clone as 67208-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 67208-1-Ig (IFIT3 antibody) at dilution of 1:300 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67208-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with IFIT3 antibody included
  • IHC staining of human spleen using 67208-1-Ig (same clone as 67208-1-PBS)

    IHC staining of human spleen using 67208-1-Ig (same clone as 67208-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 67208-1-Ig (IFIT3 antibody) at dilution of 1:300 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67208-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with IFIT3 antibody included
  • IF Staining of HepG2 using 67208-1-Ig (same clone as 67208-1-PBS)

    IF Staining of HepG2 using 67208-1-Ig (same clone as 67208-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using IFIT3 antibody (67208-1-Ig, Clone: 2C8B10 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67208-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy IFIT3 Ready-To-Use IHC Kit. IFIT3 primary antibody included.

产品信息

67208-1-PBS targets IFIT3 in WB, IF, IHC, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB,Indirect ELISA,IHC,IF Application Description
Tested Reactivity Human
Immunogen IFIT3 fusion protein Ag7518 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name IFIT3
Synonyms CIG 49, CIG49, GARG 49, IFI 60K, IFI60, IFIT 3, IFIT 4, IFIT3, IFIT4, IRG2, ISG 60, ISG60, RIG G
Calculated Molecular Weight 56 kDa
Observed Molecular Weight 60 kDa
GenBank Accession NumberBC004977
Gene Symbol IFIT3
Gene ID (NCBI) 3437
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDO14879
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

IFIT3 (IFN-induced protein with tetratricopeptide repeats 3), also known as IFIT-4, ISG-60 or RIG-G, is a 56 kDa IFN induced protein. IFIT3 has been identified to be associated with strong IFN antiviral activity. Upon RNA virus infection, IFIT3 is significantly induced, ectopic expression or knockdown of IFIT3 could, respectively, enhance or impair IFN regulatory factor 3 (IRF3)-mediated gene expression. IFIT3 thus may serve as an important modulator in innate immunity, revealing a new function of the IFIT family proteins.