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CoraLite®488-conjugated MSH6 Monoclonal antibody
MSH6 Monoclonal Antibody for FC (Intra)
Host / Isotype
Mouse / IgG2a
Reactivity
human
Applications
FC (Intra)
Conjugate
CoraLite®488 Fluorescent Dye
CloneNo.
2E10B2
验证数据展示
经过测试的应用
Positive FC (Intra) detected in | HEK-293 cells |
Positive FC detected in | HEK-293 cells |
Planning an IHC experiment? We recommend our IHCeasy MSH6 Ready-To-Use IHC Kit. MSH6 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 66172-1-Ig
推荐稀释比
Application | Dilution |
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Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.80 ug per 10^6 cells in a 100 µl suspension |
Flow Cytometry (FC) | FC : 0.80 ug per 10^6 cells in a 100 µl suspension |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL488-66172 targets MSH6 in FC (Intra) applications and shows reactivity with human samples.
Tested Applications | FC (Intra) Application Description |
Tested Reactivity | human |
Immunogen | MSH6 fusion protein Ag12645 种属同源性预测 |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Full Name | mutS homolog 6 (E. coli) |
Synonyms | G/T mismatch binding protein, GTBP, GTMBP, hMSH6, HNPCC5, HSAP, MSH6, MutS alpha 160 kDa subunit, mutS homolog 6 (E. coli), p160 |
Calculated Molecular Weight | 153 kDa |
GenBank Accession Number | BC004246 |
Gene Symbol | MSH6 |
Gene ID (NCBI) | 2956 |
RRID | AB_2919294 |
Conjugate | CoraLite®488 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 491 nm / 516 nm |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P52701 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
MSH6, also named as DNA mismatch repair protein Msh6 or GTMBP, is a 1360 amino acid protein, which contains one PWWP domain and belongs to the DNA mismatch repair MutS family. MSH6 localizes in the nucleus and is a component of the post-replicative DNA mismatch repair system. Msh2 and Msh6 form a protein complex required to repair mismatches generated during DNA replication.
实验方案
Product Specific Protocols | |
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FC protocol for CL488 MSH6 antibody CL488-66172 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |