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验证数据展示

  • IF Staining of HepG2 using CL594-17215

    IF Staining of HepG2 using CL594-17215

    Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using CoraLite®594 NLRX1 antibody (CL594-17215) at dilution of 1:800.

  • Featured Product
  • KD/KO验证

CoraLite®594-conjugated NLRX1 Polyclonal antibody

NLRX1 Polyclonal Antibody for IF/ICC
Cat No. CL594-17215

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

IF/ICC

别名

Nucleotide-binding oligomerization domain protein 9, Nucleotide-binding oligomerization domain protein 5, NOD9, NOD5, NLRX 1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite®594
规格: 

-/ -

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经过测试的应用

Positive IF/ICC detected inHepG2 cells, A549 cells
For other applications, we recommend the unconjugated version of this antibody, 17215-1-AP

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:400-1:1600
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL594-17215 targets NLRX1 in IF/ICC applications and shows reactivity with human, mouse, rat samples.

经测试应用 IF/ICC Application Description
经测试反应性 human, mouse, rat
免疫原 NLRX1 fusion protein Ag11000 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 NLR family member X1
别名 Nucleotide-binding oligomerization domain protein 9, Nucleotide-binding oligomerization domain protein 5, NOD9, NOD5, NLRX 1
计算分子量 975 aa, 108 kDa
观测分子量 100-110 kDa
GenBank蛋白编号BC013199
基因名称 NLRX1
Gene ID (NCBI) 79671
偶联类型 CoraLite®594 Fluorescent Dye
最大激发/发射波长588 nm / 604 nm
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ86UT6
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

NLRX1 (Nucleotide-binding oligomerization domain, leucine-rich repeat containing X1) is a member of the NOD-like receptor (NLR) family and is unique among NLRs due to its localization to the mitochondrial matrix. NLRX1 is a negative regulator of innate immunity, particularly in viral infections. It interacts with the mitochondrial antiviral signaling protein (MAVS) to attenuate antiviral responses. NLRX1 has been implicated in various diseases, including multiple sclerosis, colorectal cancer, and ischemia-reperfusion injury. Its role in controlling inflammation and mitochondrial function makes it a potential therapeutic target.

实验方案

Product Specific Protocols
IF protocol for CL594 NLRX1 antibody CL594-17215Download protocol
Standard Protocols
Click here to view our Standard Protocols