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  • Featured Product
  • KD/KO Validated

CoraLite® Plus 488-conjugated TNNC1 Polyclonal antibody

TNNC1 Polyclonal Antibody for IF/ICC

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF/ICC

Conjugate

CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-13504

Print datasheet

Synonyms

CMD1Z, TN C, TNC, TNNC, TNNC1, troponin C type 1 (slow)

验证数据展示

  • IF Staining of U2OS using CL488-13504

    IF Staining of U2OS using CL488-13504

    Immunofluorescent analysis of (-20°C Methanol) fixed U2OS cells using CoraLite® Plus 488 TNNC1 antibody (CL488-13504) at dilution of 1:200.

经过测试的应用

Positive IF/ICC detected inU2OS cells
For other applications, we recommend the unconjugated version of this antibody, 13504-1-AP

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-13504 targets TNNC1 in IF/ICC applications and shows reactivity with human, mouse, rat samples.

Tested Applications IF/ICC Application Description
Tested Reactivity human, mouse, rat
Immunogen TNNC1 fusion protein Ag4339 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name troponin C type 1 (slow)
Synonyms CMD1Z, TN C, TNC, TNNC, TNNC1, troponin C type 1 (slow)
Calculated Molecular Weight 161 aa, 18 kDa
Observed Molecular Weight 18 kDa
GenBank Accession NumberBC030244
Gene Symbol TNNC1
Gene ID (NCBI) 7134
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP63316
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. TnC plays an important role in excitation-contraction coupling and is the primary target of compounds such as levosimendan that augment Ca2+ responsiveness of the thin filament.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 TNNC1 antibody CL488-13504Download protocol
Standard Protocols
Click here to view our Standard Protocols