- Featured Product
- KD/KO Validated
CoraLite®594-conjugated Aquaporin 4 Polyclonal antibody
Aquaporin 4 Polyclonal Antibody for IF-P
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
IF-P
Conjugate
CoraLite®594 Fluorescent Dye
验证数据展示
经过测试的应用
Positive IF-P detected in | rat brain tissue, mouse brain tissue |
For other applications, we recommend the unconjugated version of this antibody, 16473-1-AP
推荐稀释比
Application | Dilution |
---|---|
Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
The immunogen of CL594-16473 is Aquaporin 4 Fusion Protein expressed in E. coli.
Tested Applications | IF-P Application Description |
Tested Reactivity | human, mouse, rat |
Immunogen | Aquaporin 4 fusion protein Ag9561 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | aquaporin 4 |
Synonyms | AQP 4, AQP4, aquaporin 4, HMIWC2, MIWC, WCH4 |
Calculated Molecular Weight | 323 aa, 35 kDa |
Observed Molecular Weight | 35-37 kDa, 32-34 kDa |
GenBank Accession Number | BC022286 |
Gene Symbol | AQP4 |
Gene ID (NCBI) | 361 |
RRID | AB_2919831 |
Conjugate | CoraLite®594 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 588 nm / 604 nm |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P55087 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Aquaporins are specialized water transport channels in plasma membranes of water-permeable tissues. Aquaporin-4 (AQP4) is the most abundant water channel in the human central nervous system and is important to fluid movements in brain. Aquaporin-4 exists as two isoforms, a long (M1) isoform with translation initiation at Met-1, and a shorter (M23) isoform with translation initiation at Met-23, with molecular weights around 35-37 kDa and 32-34 kDa, respectively.
实验方案
Product Specific Protocols | |
---|---|
IF protocol for CL594 Aquaporin 4 antibody CL594-16473 | Download protocol |
Standard Protocols | |
---|---|
Click here to view our Standard Protocols |