验证数据展示
经过测试的应用
Positive IF-P detected in | mouse brain tissue |
推荐稀释比
应用 | 推荐稀释比 |
---|---|
Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
发表文章中的应用
IF | See 2 publications below |
产品信息
CL647-16473 targets Aquaporin 4 in IF-P applications and shows reactivity with human, mouse, rat samples.
经测试应用 | IF-P Application Description |
文献引用应用 | IF |
经测试反应性 | human, mouse, rat |
文献引用反应性 | mouse |
免疫原 | Aquaporin 4 fusion protein Ag9561 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | Aquaporin 4 |
别名 | AQP 4, AQP4, aquaporin 4, HMIWC2, MIWC, WCH4 |
计算分子量 | 323 aa, 35 kDa |
观测分子量 | 35-37 kDa, 32-34 kDa |
GenBank蛋白编号 | BC022286 |
基因名称 | Aquaporin 4 |
Gene ID (NCBI) | 361 |
RRID | AB_2920230 |
偶联类型 | CoraLite® Plus 647 Fluorescent Dye |
最大激发/发射波长 | 654 nm / 674 nm |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P55087 |
储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Aquaporins are specialized water transport channels in plasma membranes of water-permeable tissues. Aquaporin-4 (AQP4) is the most abundant water channel in the human central nervous system and is important to fluid movements in brain. Aquaporin-4 exists as two isoforms, a long (M1) isoform with translation initiation at Met-1, and a shorter (M23) isoform with translation initiation at Met-23, with molecular weights around 35-37 kDa and 32-34 kDa, respectively.
实验方案
Product Specific Protocols | |
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IF protocol for CL Plus 647 Aquaporin 4 antibody CL647-16473 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
发表文章
Species | Application | Title |
---|---|---|
J Clin Invest APOE-ε4 synergizes with sleep disruption to accelerate Aβ deposition and Aβ-associated tau seeding and spreading | ||
Cell Rep Integrative multi-omic profiling of adult mouse brain endothelial cells and potential implications in Alzheimer's disease |