CoraLite®555-conjugated Phospho-RIPK1 (Ser161) Monoclonal antibody
Phospho-RIPK1 (Ser161) Monoclonal Antibody for FC (Intra)
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
FC (Intra)
Conjugate
CoraLite®555 Fluorescent Dye
CloneNo.
1B2G1
验证数据展示
For other applications, we recommend the unconjugated version of this antibody, 66854-1-Ig
产品信息
CL555-66854 targets Phospho-RIPK1 (Ser161) in FC (Intra) applications and shows reactivity with Human samples.
| Tested Applications | FC (Intra) Application Description |
| Tested Reactivity | Human |
| Immunogen | Peptide 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| Synonyms | Cell death protein RIP, FLJ39204, Receptor interacting protein 1, RIP, RIP 1, RIP1, RIPK1 |
| Calculated Molecular Weight | 76 kDa |
| Observed Molecular Weight | 74 kDa, 45 kDa |
| GenBank Accession Number | NM_003804 |
| Gene Symbol | RIPK1 |
| Gene ID (NCBI) | 8737 |
| Conjugate | CoraLite®555 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 557 nm / 570 nm |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | Q13546 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
RIPK1(Receptor-interacting serine/threonine-protein kinase 1) is primarily involved in mediating TNF-R1-induced cell activation, apoptosis and necroptosis and belongs to a novel class of kinases thatfunction in cell survival and cell death mechanisms(PMID:22685397 ).It has 2 isoforms produced by alternative splicing.It also can exist as the protein with lower molecular weight about 25kd and 45kd in HAEC and HUVEC(PMID:22685397).