CoraLite®488-conjugated TOM20 Monoclonal antibody

TOM20 Monoclonal Antibody for FC (Intra), IF

Host / Isotype

Mouse / IgG2b

Reactivity

Human and More (1)

Applications

FC (Intra), IF

Conjugate

CoraLite®488 Fluorescent Dye

CloneNo.

1D6F5

Cat No : CL488-66777

Print datasheet

Synonyms

KIAA0016, MAS20, Mitochondrion Marker, MOM19, TOM20, TOMM20



经过测试的应用

Positive IF detected inHepG2 cells
Positive FC detected inHeLa cells
For other applications, we recommend the unconjugated version of this antibody, 66777-1-Ig

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

产品信息

CL488-66777 targets TOM20 in IF, FC (Intra) applications and shows reactivity with Human samples.

Tested Applications FC (Intra), IF
Tested Reactivity Human
Cited Reactivityhuman
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen TOM20 fusion protein Ag2378 种属同源性预测
Full Name translocase of outer mitochondrial membrane 20 homolog (yeast)
Synonyms KIAA0016, MAS20, Mitochondrion Marker, MOM19, TOM20, TOMM20
Calculated molecular weight 145 aa, 16 kDa
Observed molecular weight 16 kDa
GenBank accession numberBC000882
Gene symbol TOMM20
UniprotQ15388
Gene ID (NCBI) 9804
RRIDAB_2919367
Conjugate CoraLite®488 Fluorescent Dye
Excitation/Emission maxima wavelengths488 nm / 515 nm
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

TOM20, also named as KIAA0016, belongs to the Tom20 family. It is a central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22, TOM20 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore. TOM20 is characterized as major docking receptors to mediate the recognition by different mechanisms.

实验方案

Product Specific Protocols
IF protocol for CL488 TOM20 antibody CL488-66777Download protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
human

Cell Mol Life Sci

Restricting α-synuclein transport into mitochondria by inhibition of α-synuclein-VDAC complexation as a potential therapeutic target for Parkinson's disease treatment.

Authors - Megha Rajendran