GSK3 signaling: Pathway Poster
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All the posters in the Proteintech library are available in PDF format or can be requested as a hard copy.
GSK3 Pathway Overview
GSK3 (Glycogen Synthase Kinase-3) is a signaling mediator involved in a variety of different signaling pathways including WNT, growth factors, insulin, and Hedgehog pathways.
Recent studies have shown GSK3 dysregulation to be associated with a number of diseases, including Type II diabetes, Alzheimer’s disease, inflammation, cancer, and bipolar disorder (D Wu and W Pan. 2010). It has also been suggested that inhibition of GSK has the capacity to undergo oxidative metabolism and has protective effects on neurons, counteracting ischemic neuronal death (Valerio et al., 2011).
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Download the GSK3 signaling pathway poster here |
Related Antibodies
Antibodies | GBP1 |
AKT1 | GSK3A |
AXIN1 | GSK3B |
beta-Catenin | PI3K p110 (alpha) |
eIF2A | PI3K p110 (beta) |
ERK1/2 | PI3K p110 (gamma) |
Browse more pathway posters here |
References
D Wu and W Pan. (2010). GSK3: a multifaceted kinase in Wnt signaling. Trends Biochem Sci. 35 (3), p161–168.